DrugRepV_0047 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0049 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0052 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0053 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0058 | Mericitabine | Antiviral | Hepatitis C virus | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Investigational | 28912011 |
DrugRepV_0059 | Mericitabine | Antiviral | Hepatitis C virus | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Investigational | 28912011 |
DrugRepV_0062 | Mericitabine | Antiviral | Hepatitis C virus | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Investigational | 28912011 |
DrugRepV_0063 | Mericitabine | Antiviral | Hepatitis C virus | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Investigational | 28912011 |
DrugRepV_0075 | Bromocriptine | Nervous System | Parkinson disease | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28185815 |
DrugRepV_0078 | Intron A | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28185815 |
DrugRepV_0081 | Avonex | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28185815 |
DrugRepV_0084 | Rebif | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28185815 |
DrugRepV_0087 | Betaferon | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28185815 |
DrugRepV_0090 | Imukin | NA | NA | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 28185815 |
DrugRepV_0748 | Favipiravir | Antiviral | Influenza virus | Nipah virus | rNiV-Gluc-eGFP | NA | Cytopathic effect (CPE) assay | Decrease (4 Log (pfu/ml)) | Investigational | 29765101 |
DrugRepV_1992 | Emetine Dihydrochloride Hydrate | Antiparasitic products, Insectisides and Repellents | Protozoal disease | Middle East respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24841273 |
DrugRepV_1993 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1994 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1995 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_1996 | Amodiaquine Dihydrochloride dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_1997 | Gemcitabine Hydrochloride | Antineoplastic and Immunomodulating Agents | Ovarian cancer | Non-small cell lung cance | Adenocarcinoma of the pancreas | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1998 | Tamoxifen Citrate | Antineoplastic and Immunomodulating Agents | Breast cancer | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1999 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_2000 | Terconazole | Genito Urinary System and Sex Hormones | Candidiasis (a yeast-like fungal infection) of the vulva and vagina | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2001 | Anisomycin | Antibacterial | Bacterial infections | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 24841273 |
DrugRepV_2002 | Cycloheximide | Antibacterial | Bacterial and fungal infections | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24841273 |
DrugRepV_2003 | Benztropine Mesylate | Nervous System | Parkinson disease | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2004 | Fluspirilene | Nervous System | Schizophrenia | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_2005 | Thiothixene | Nervous System | Schizophrenia | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2006 | Fluphenazine Hydrochloride | Nervous System | Psychosis | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2007 | Promethazine Hydrochloride | Respiratory System | Allergic disorders | Nausea/vomiting | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_2008 | Astemizole | Respiratory System | Allergies | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Withdrawn | 24841273 |
DrugRepV_2009 | Chlorphenoxamine Hydrochloride | Respiratory System | Parkinson's | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Withdrawn | 24841273 |
DrugRepV_2010 | Chlorpromazine Hydrochloride | Nervous System | Psychosis | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2011 | Triflupromazine Hydrochloride | Nervous System | Psychosis | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2012 | Clomipramine Hydrochloride | Nervous System | Psychosis | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2013 | Imatinib Mesylate | Antineoplastic and Immunomodulating Agents | Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_2014 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (90 %) | Approved | 24841273 |
DrugRepV_2128 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27163257 |
DrugRepV_2130 | Favipiravir | Antiviral | Influenza virus | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27163257 |
DrugRepV_2132 | 2-C-Methylcytidine | NA | Hepatitis C virus | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 27163257 |
DrugRepV_2134 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 27163257 |
DrugRepV_2140 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2142 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2144 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2146 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2148 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2150 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2152 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2154 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_3156 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 14670584 |
DrugRepV_3157 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3158 | Glycyrrhizin | Alimentary Tract and Metabolism | Chronic hepatitis | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Experimental | 14670584 |
DrugRepV_3159 | Iota-carrageenan | Plant extract | Common Cold | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 14670584 |
DrugRepV_3160 | Fucoidan | NA | NA | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3161 | Dextran Sulphate | Blood and Blood Forming Organs | NA | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 14670584 |
DrugRepV_3162 | IFN-alpha2a | Antineoplastic and Immunomodulating Agents | Hepatitis C virus | Hairy cell leukemia | AIDS-related Kaposi's sarcoma | Leukemia | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 14670584 |
DrugRepV_3163 | IFN-alpha2b | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 14670584 |
DrugRepV_3164 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (1.8 Log) | Approved | 14670584 |
DrugRepV_3165 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (1.8 Log) | NA | 14670584 |
DrugRepV_3166 | Glycyrrhizin | Alimentary Tract and Metabolism | Chronic hepatitis | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (5.2 Log) | Approved, Experimental | 14670584 |
DrugRepV_3167 | IFN-alpha2b | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (5.4 Log) | Approved | 14670584 |
DrugRepV_3168 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | Approved | 14670584 |
DrugRepV_3169 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | NA | 14670584 |
DrugRepV_3170 | Glycyrrhizin | Alimentary Tract and Metabolism | Chronic hepatitis | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | Approved, Experimental | 14670584 |
DrugRepV_3171 | IFN-alpha2b | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | Approved | 14670584 |
DrugRepV_3172 | IFN-alpha2b-Ribavirin | NA | NA | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3261 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3262 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3263 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3264 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3265 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3266 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3267 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res_p7 C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3268 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res_p7 C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3269 | Favipiravir | Antiviral | Influenza virus | Chikungunya virus | Favipiravir_res_p7 C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 24951535 |
DrugRepV_3270 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3271 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3272 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3363 | Peg-interferon A-2b | Antineoplastic and Immunomodulating Agents | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | HKU-39849 | NA | Cytopathic effect (CPE) assay | Decrease (100 %) | Approved | 23620378 |
DrugRepV_3364 | Peg-interferon A-2b | Antineoplastic and Immunomodulating Agents | Hepatitis C virus | Middle East respiratory syndrome coronavirus | HKU-39849 | NA | Cytopathic effect (CPE) assay | Decrease (100 %) | Approved | 23620378 |
DrugRepV_3431 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Hongkong/4801/2014 (H3N2) | | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3737 | OSU-03012 | Anticancer | Brain cancer | Crimean-Congo hemorrhagic fever virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25986249 |
DrugRepV_3861 | Favipiravir | Antiviral | Influenza virus | Rift Valley fever virus | MP12 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27736754 |
DrugRepV_3867 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3868 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3869 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3870 | BCX4430 | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3871 | BCX4430 | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3872 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3873 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3874 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3875 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3876 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3877 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3878 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3879 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3880 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3881 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3882 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_4190 | Phorbol | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4191 | Phorbol-12-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 25970561 |
DrugRepV_4192 | Phorbol-12-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4193 | Phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4194 | Phorbol-13-butyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4195 | Pphorbol-13-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4196 | Phorbol-13-tetradecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4197 | Phorbol-12,13-diacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4198 | Phorbol-12,13-dibutyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4199 | Phorbol-12,13- dihexanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4200 | Phorbol-12,13-didecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4201 | 4α-phorbol-12,13-didecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4202 | 12-O-tetradecanoylphorbol-13-acetate | NA | Cancer | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase II | 25970561 |
DrugRepV_4203 | 12-O-tetradecanoyl-4?-phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4204 | 12-O- tiglylphorbol-13-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4205 | 12-O-(N-methylanthranilate) phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4206 | Phorbol-13,20-diacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4207 | 12,13-O,O-dinonanoylphorbol-20-homovanillate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4208 | 12-O-phenylacetyl-13-O-acetylphorbol-20-homovanillate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4209 | Phorbol-12,13,20-triacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4210 | 20-oxo-20-deoxyphorbol-12,13-dibutyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4211 | 12-O-tetradecanoyl-20-oxo-20-deoxyphorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4212 | 12-deoxyphorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4213 | 13-O-isobutyryl-12-deoxyphorbol-20-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4214 | 13-O-phenylacetyl-12-deoxyphorbol-20-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4215 | Ingenol | Dermatologicals | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4216 | Ingenol-3-mebutate | Dermatologicals | Actinic keratosis | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 25970561 |
DrugRepV_4217 | Ingenol-3,20-dibenzoate | Dermatologicals | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4218 | Resiniferatoxin | NA | Interstitial cystitis and urinary incontinence | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 25970561 |
DrugRepV_4219 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 25970561 |
DrugRepV_4576 | Glycyrrhizin | Alimentary Tract and Metabolism | Chronic hepatitis | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Experimental | 15715493 |
DrugRepV_4577 | Glycyrrhetinic Acid | NA | Apparent mineralocorticoid excess syndrome | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 15715493 |
DrugRepV_4578 | (2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4579 | (2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4580 | (2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptame | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4581 | 6-{[(3S,6aR,6bS,8aS,11S,14bS)-4,4,6a,6b,8a,11,14b-heptamethyl-11-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-3,4-dihydroxy-N-[(2S)-4-methyl-1-oxopentan-2-yl]-5-[(3 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4582 | butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4583 | methyl (2S)-2-(2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4584 | (4S)-4-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4585 | butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a, | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4586 | (2S,4aS,6aS,6bR,10S,12aS)-10-{[4,5-dihydroxy-6-(2-hydroxyacetyl)-3-{[3,4,5-trihydroxy-6-(2-hydroxyacetyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carbo | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4587 | (2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]-3-({3,4,5-trihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,1 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4588 | 5-{6-[(2-{[(3S,6aR,6bS,8aS,11S,14bS)-11-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-6-(2,4-dioxo-1,2,3,4-tetrahydropyrimidi | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4589 | methyl (2S,4aS,6aS,6bR,10S,12aS)-10-({6-[(hydrazinecarbonyl)carbonyl]-3-({6-[(hydrazinecarbonyl)carbonyl]-3,4,5-trihydroxyoxan-2-yl}oxy)-4,5-dihydroxyoxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b, | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4590 | methyl (2S,4aS,6aS,6bR,10S,12aS)-10-{[6-(2-azidoacetyl)-3-{[6-(2-azidoacetyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-ca | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4591 | 2-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4592 | 4-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-oxobutanoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4614 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 19853271 |
DrugRepV_4615 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 19853271 |
DrugRepV_4616 | Promazine | Nervous System | Psychomotor agitation | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Vet approved | 19853271 |
DrugRepV_4617 | Promazine | Nervous System | Psychomotor agitation | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Vet approved | 19853271 |
DrugRepV_4618 | Calpain VI inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4619 | Calpain VI inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4620 | Calpain IV inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4621 | Calpain IV inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4622 | Infergen | Anticancer | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcom | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 19853271 |
DrugRepV_4623 | Infergen | Anticancer | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcom | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 19853271 |
DrugRepV_4624 | Ampligen | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4625 | Ampligen | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4626 | UDA | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4627 | UDA | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4628 | EP128533 | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4629 | EP128533 | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4634 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4635 | ethyl (2E,4S)-4-[(2S)-3-(4-fluorophenyl)-2-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)formamido]butanamido]propanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4636 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-3-phenylpropanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4637 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4638 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(tert-butoxy)butanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4639 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (6.4 Log10) | NA | 16884309 |
DrugRepV_4640 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease | NA | 16884309 |
DrugRepV_4641 | 5CI-IS-AC | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4642 | SPIII-5H | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4643 | SPIII-5Cl | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4644 | SPIII-5Br | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4645 | SPIII-5F | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4646 | SPIII-5Me | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4647 | SPIII-NA | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4714 | Nutlin-3 | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4715 | Hydroxyzine pamoate | Nervous System | Anxiety | Tension | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4716 | Amodiaquine Dihydrochloride | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4717 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 29795047 |
DrugRepV_4718 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational, Vet approved | 29795047 |
DrugRepV_4719 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 29795047 |
DrugRepV_4720 | Saracatinib | Anticancer | Osteosarcoma | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 29795047 |
DrugRepV_4721 | Sotrastaurin | Anticancer | Uveal Melanoma | Richter Syndrome | Prolymphocytic Leukemia | Recurrent Mantle Cell Lymphoma Recurrent Small Lymphocytic Lymphoma | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 29795047 |
DrugRepV_4722 | Acetophenazine Maleate | Nervous System | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 29795047 |
DrugRepV_4723 | Dosulepin Hydrochloride | Nervous System | Psychosis | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 29795047 |
DrugRepV_4724 | Methotrimeprazine Maleate Salt | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 29795047 |
DrugRepV_4725 | N1-(4-pyridyl)-2-chloro-5-nitrobenzamide | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_5953 | NITD008 | Antiviral | NA | Dengue virus | New Guinea C | | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19918064 |
DrugRepV_5963 | NITD008 | Antiviral | NA | Dengue virus | New Guinea C | | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19918064 |
DrugRepV_5969 | ZX-2401 | NA | Rhinovirus 1A | Rhinovirus 30 | Rhinovirus 13 | Rhinovirus 8 | Rhinovirus 2 | Dengue virus | New Guinea | | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16199098 |
DrugRepV_7241 | Favipiravir | Antiviral | Influenza virus | Yellow fever virus | 17D | | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27736754 |
DrugRepV_7330 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Cytopathic effect (CPE) assay | Decrease | NA | 27563890 |
DrugRepV_7331 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Cytopathic effect (CPE) assay | Decrease | NA | 27563890 |
DrugRepV_7387 | SCH16-Ribavirin | NA | NA | Japanese encephalitis virus | P20778 | | Cytopathic effect (CPE) assay | Decrease | NA | 22738253 |
DrugRepV_7388 | SCH16-Mycophenolic acid | NA | NA | Japanese encephalitis virus | P20778 | | Cytopathic effect (CPE) assay | Decrease | NA | 22738253 |
DrugRepV_7525 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7526 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/MO/14-18949 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7527 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/MO/14-18947 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7528 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/IL/14-18952 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7529 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/IL/14-18956 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7530 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7531 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7532 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7533 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7608 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7609 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7617 | Remdesivir | Antiviral | Hepatitis C | Ebola | SARS Coronavirus-2 | SARS-CoV-2 (?CoV/KOR/KCDC03/2020 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 32438446 |
DrugRepV_7647 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7648 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7672 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32511355 |
DrugRepV_7673 | ROC-325 | NA | NA | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32511355 |
DrugRepV_7674 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 32511355 |
DrugRepV_7675 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32511355 |
DrugRepV_7676 | Hycanthone | Antischistosomal | Parasitic infections | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 32511355 |
DrugRepV_7677 | Clomipramine | Nervous System | Depression, schizophrenia, Tourette disorder | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32511355 |
DrugRepV_8325 | Remdesivir | Antiviral | Hepatitis C | Ebola | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 32429580 |
DrugRepV_8326 | Tenofovir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 32429580 |
DrugRepV_8327 | 4-ethynyl-2-fluoro-2-deoxyadenosine | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8328 | Alovudine | NA | HIV | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 32429580 |
DrugRepV_8329 | 5-O-(12-thioethydodecanoyl)FLT | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8330 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32429580 |
DrugRepV_8331 | 5-O-(tetradecanoyl)3TC | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8332 | Emtricitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32429580 |
DrugRepV_8333 | 5-O-(tetradecanoyl)FTC | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8459 | Berberine | NA | Parasitic and fungal infection | Enterovirus | H | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8460 | Berberine | NA | Parasitic and fungal infection | Enterovirus | SHZH98 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8461 | Berberine | NA | Parasitic and fungal infection | Enterovirus | JS-52 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8462 | Berberine | NA | Parasitic and fungal infection | Enterovirus | BrCr | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8463 | Pirodavir | NA | Picronavirus infection | Enterovirus | H | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8464 | Pirodavir | NA | Picronavirus infection | Enterovirus | SHZH98 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8465 | Pirodavir | NA | Picronavirus infection | Enterovirus | JS-52 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8466 | Pirodavir | NA | Picronavirus infection | Enterovirus | BrCr | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |