DrugRepV Browse Page


DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Cytopathic effect (CPE) assay are 234




DrugRepV_ID Antiviral Name
Drug type
Primary Indication
Secondary Indication
Strain
Pathways
Assay
Activity
Clinical Status
References
DrugRepV_0047Sofosbuvir
Antiinfectives For Systemic Use
Hepatitis C virus | Acquired immunodeficiency syndrome
Zika virus
H/PF/2013
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28912011
DrugRepV_0049Sofosbuvir
Antiinfectives For Systemic Use
Hepatitis C virus | Acquired immunodeficiency syndrome
Zika virus
ZIKVNL00013
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28912011
DrugRepV_0052Sofosbuvir
Antiinfectives For Systemic Use
Hepatitis C virus | Acquired immunodeficiency syndrome
Zika virus
H/PF/2013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Approved
28912011
DrugRepV_0053Sofosbuvir
Antiinfectives For Systemic Use
Hepatitis C virus | Acquired immunodeficiency syndrome
Zika virus
ZIKVNL00013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Approved
28912011
DrugRepV_0058Mericitabine
Antiviral
Hepatitis C virus
Zika virus
H/PF/2013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Investigational
28912011
DrugRepV_0059Mericitabine
Antiviral
Hepatitis C virus
Zika virus
ZIKVNL00013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Investigational
28912011
DrugRepV_0062Mericitabine
Antiviral
Hepatitis C virus
Zika virus
H/PF/2013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Investigational
28912011
DrugRepV_0063Mericitabine
Antiviral
Hepatitis C virus
Zika virus
ZIKVNL00013
NA
Cytopathic effect (CPE) assay
No significant effect (0 %)
Investigational
28912011
DrugRepV_0075Bromocriptine
Nervous System
Parkinson disease
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28185815
DrugRepV_0078Intron A
Antineoplastic and Immunomodulating Agents
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28185815
DrugRepV_0081Avonex
Antineoplastic and Immunomodulating Agents
Multiple sclerosis
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28185815
DrugRepV_0084Rebif
Antineoplastic and Immunomodulating Agents
Multiple sclerosis
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28185815
DrugRepV_0087Betaferon
Antineoplastic and Immunomodulating Agents
Multiple sclerosis
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28185815
DrugRepV_0090Imukin
NA
NA
Zika virus
Puerto Rico strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
28185815
DrugRepV_0748Favipiravir
Antiviral
Influenza virus
Nipah virus
rNiV-Gluc-eGFP
NA
Cytopathic effect (CPE) assay
Decrease (4 Log (pfu/ml))
Investigational
29765101
DrugRepV_1992Emetine Dihydrochloride Hydrate
Antiparasitic products, Insectisides and Repellents
Protozoal disease
Middle East respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24841273
DrugRepV_1993Chloroquine Diphosphate
Antiparasitic products, Insectisides and Repellents
Parasitic infections
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_1994Hydroxychloroquine Sulfate
Antiparasitic products, Insectisides and Repellents
Malaria
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_1995Mefloquine
Antiparasitic products, Insectisides and Repellents
Malaria
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
24841273
DrugRepV_1996Amodiaquine Dihydrochloride dihydrate
Antiparasitic products, Insectisides and Repellents
Malaria
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
24841273
DrugRepV_1997Gemcitabine Hydrochloride
Antineoplastic and Immunomodulating Agents
Ovarian cancer | Non-small cell lung cance | Adenocarcinoma of the pancreas
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_1998Tamoxifen Citrate
Antineoplastic and Immunomodulating Agents
Breast cancer
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_1999Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
24841273
DrugRepV_2000Terconazole
Genito Urinary System and Sex Hormones
Candidiasis (a yeast-like fungal infection) of the vulva and vagina
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2001Anisomycin
Antibacterial
Bacterial infections
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
24841273
DrugRepV_2002Cycloheximide
Antibacterial
Bacterial and fungal infections
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24841273
DrugRepV_2003Benztropine Mesylate
Nervous System
Parkinson disease
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2004Fluspirilene
Nervous System
Schizophrenia
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
24841273
DrugRepV_2005Thiothixene
Nervous System
Schizophrenia
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2006Fluphenazine Hydrochloride
Nervous System
Psychosis
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2007Promethazine Hydrochloride
Respiratory System
Allergic disorders | Nausea/vomiting
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
24841273
DrugRepV_2008Astemizole
Respiratory System
Allergies
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Withdrawn
24841273
DrugRepV_2009Chlorphenoxamine Hydrochloride
Respiratory System
Parkinson's
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Withdrawn
24841273
DrugRepV_2010Chlorpromazine Hydrochloride
Nervous System
Psychosis
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2011Triflupromazine Hydrochloride
Nervous System
Psychosis
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2012Clomipramine Hydrochloride
Nervous System
Psychosis
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2013Imatinib Mesylate
Antineoplastic and Immunomodulating Agents
Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
24841273
DrugRepV_2014Dasatinib
Antineoplastic and Immunomodulating Agents
Cancer
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (90 %)
Approved
24841273
DrugRepV_2128Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
MR766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27163257
DrugRepV_2130Favipiravir
Antiviral
Influenza virus
Zika virus
MR766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27163257
DrugRepV_21322-C-Methylcytidine
NA
Hepatitis C virus
Zika virus
MR766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
27163257
DrugRepV_21347-deaza-2-C-methyl-D-adenosine
NA
Viral infection
Zika virus
MR766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
27163257
DrugRepV_2140BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Puerto Rican strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2142BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Puerto Rican strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2144BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Puerto Rican strain PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2146BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2148BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2150BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2152BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_2154BCX4430 Dihydrochloride
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase I
27838352
DrugRepV_3156Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
14670584
DrugRepV_31576-Azauridine
NA
Cancer
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
14670584
DrugRepV_3158Glycyrrhizin
Alimentary Tract and Metabolism
Chronic hepatitis
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Experimental
14670584
DrugRepV_3159Iota-carrageenan
Plant extract
Common Cold
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
14670584
DrugRepV_3160Fucoidan
NA
NA
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
14670584
DrugRepV_3161Dextran Sulphate
Blood and Blood Forming Organs
NA
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
14670584
DrugRepV_3162IFN-alpha2a
Antineoplastic and Immunomodulating Agents
Hepatitis C virus | Hairy cell leukemia | AIDS-related Kaposi's sarcoma | Leukemia
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
14670584
DrugRepV_3163IFN-alpha2b
Antineoplastic and Immunomodulating Agents
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
14670584
DrugRepV_3164Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (1.8 Log)
Approved
14670584
DrugRepV_31656-Azauridine
NA
Cancer
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (1.8 Log)
NA
14670584
DrugRepV_3166Glycyrrhizin
Alimentary Tract and Metabolism
Chronic hepatitis
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (5.2 Log)
Approved, Experimental
14670584
DrugRepV_3167IFN-alpha2b
Antineoplastic and Immunomodulating Agents
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (5.4 Log)
Approved
14670584
DrugRepV_3168Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (99 %)
Approved
14670584
DrugRepV_31696-Azauridine
NA
Cancer
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (99 %)
NA
14670584
DrugRepV_3170Glycyrrhizin
Alimentary Tract and Metabolism
Chronic hepatitis
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (99 %)
Approved, Experimental
14670584
DrugRepV_3171IFN-alpha2b
Antineoplastic and Immunomodulating Agents
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (99 %)
Approved
14670584
DrugRepV_3172IFN-alpha2b-Ribavirin
NA
NA
Chikungunya virus
Ross C347
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
14670584
DrugRepV_3261Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res C1-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3262Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res C2-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3263Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res C3-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3264T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res C1-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3265T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res C2-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3266T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res C3-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3267Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res_p7 C1-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3268Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res_p7 C2-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3269Favipiravir
Antiviral
Influenza virus
Chikungunya virus
Favipiravir_res_p7 C3-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
24951535
DrugRepV_3270T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res_p7 C1-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3271T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res_p7 C2-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3272T-1105
NA
Zika virus
Chikungunya virus
Favipiravir_res_p7 C3-CHIKV 899
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
24951535
DrugRepV_3363Peg-interferon A-2b
Antineoplastic and Immunomodulating Agents
Hepatitis C virus
Severe acute respiratory syndrome coronavirus
HKU-39849
NA
Cytopathic effect (CPE) assay
Decrease (100 %)
Approved
23620378
DrugRepV_3364Peg-interferon A-2b
Antineoplastic and Immunomodulating Agents
Hepatitis C virus
Middle East respiratory syndrome coronavirus
HKU-39849
NA
Cytopathic effect (CPE) assay
Decrease (100 %)
Approved
23620378
DrugRepV_3431Dapivirine
NA
Acquired immunodeficiency syndrome
Influenza virus
A/Hongkong/4801/2014 (H3N2)
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
28778830
DrugRepV_3737OSU-03012
Anticancer
Brain cancer
Crimean-Congo hemorrhagic fever virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25986249
DrugRepV_3861Favipiravir
Antiviral
Influenza virus
Rift Valley fever virus
MP12
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27736754
DrugRepV_3867BCX4430
NA
Ebola virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3868BCX4430
NA
Ebola virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3869BCX4430
NA
Ebola virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3870BCX4430
NA
Ebola virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3871BCX4430
NA
Ebola virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3872BCX4430
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3873BCX4430
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3874BCX4430
NA
Ebola virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27838352
DrugRepV_3875Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3876Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3877Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Puerto Rican PRVABC-59
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3878Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3879Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Malaysian P 6-740
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3880Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3881Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_3882Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Zika virus
Ugandan MR-766
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
27838352
DrugRepV_4190Phorbol
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4191Phorbol-12-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
25970561
DrugRepV_4192Phorbol-12-decanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4193Phorbol-13-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4194Phorbol-13-butyrate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4195Pphorbol-13-decanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4196Phorbol-13-tetradecanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4197Phorbol-12,13-diacetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4198Phorbol-12,13-dibutyrate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4199Phorbol-12,13- dihexanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4200Phorbol-12,13-didecanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_42014α-phorbol-12,13-didecanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_420212-O-tetradecanoylphorbol-13-acetate
NA
Cancer
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Phase II
25970561
DrugRepV_420312-O-tetradecanoyl-4?-phorbol-13-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_420412-O- tiglylphorbol-13-decanoate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_420512-O-(N-methylanthranilate) phorbol-13-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4206Phorbol-13,20-diacetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_420712,13-O,O-dinonanoylphorbol-20-homovanillate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_420812-O-phenylacetyl-13-O-acetylphorbol-20-homovanillate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4209Phorbol-12,13,20-triacetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_421020-oxo-20-deoxyphorbol-12,13-dibutyrate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_421112-O-tetradecanoyl-20-oxo-20-deoxyphorbol-13-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_421212-deoxyphorbol-13-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_421313-O-isobutyryl-12-deoxyphorbol-20-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_421413-O-phenylacetyl-12-deoxyphorbol-20-acetate
NA
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4215Ingenol
Dermatologicals
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4216Ingenol-3-mebutate
Dermatologicals
Actinic keratosis
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
25970561
DrugRepV_4217Ingenol-3,20-dibenzoate
Dermatologicals
NA
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
25970561
DrugRepV_4218Resiniferatoxin
NA
Interstitial cystitis and urinary incontinence
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
25970561
DrugRepV_4219Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Chikungunya virus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
25970561
DrugRepV_4576Glycyrrhizin
Alimentary Tract and Metabolism
Chronic hepatitis
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Experimental
15715493
DrugRepV_4577Glycyrrhetinic Acid
NA
Apparent mineralocorticoid excess syndrome
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
15715493
DrugRepV_4578(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4579(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4580(2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptame
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_45816-{[(3S,6aR,6bS,8aS,11S,14bS)-4,4,6a,6b,8a,11,14b-heptamethyl-11-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-3,4-dihydroxy-N-[(2S)-4-methyl-1-oxopentan-2-yl]-5-[(3
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4582butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4583methyl (2S)-2-(2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4584(4S)-4-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4585butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4586(2S,4aS,6aS,6bR,10S,12aS)-10-{[4,5-dihydroxy-6-(2-hydroxyacetyl)-3-{[3,4,5-trihydroxy-6-(2-hydroxyacetyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carbo
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4587(2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]-3-({3,4,5-trihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,1
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_45885-{6-[(2-{[(3S,6aR,6bS,8aS,11S,14bS)-11-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-6-(2,4-dioxo-1,2,3,4-tetrahydropyrimidi
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4589methyl (2S,4aS,6aS,6bR,10S,12aS)-10-({6-[(hydrazinecarbonyl)carbonyl]-3-({6-[(hydrazinecarbonyl)carbonyl]-3,4,5-trihydroxyoxan-2-yl}oxy)-4,5-dihydroxyoxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4590methyl (2S,4aS,6aS,6bR,10S,12aS)-10-{[6-(2-azidoacetyl)-3-{[6-(2-azidoacetyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-ca
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_45912-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}benzoic acid
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_45924-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-oxobutanoic acid
NA
NA
Severe acute respiratory syndrome coronavirus
FFM1
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
15715493
DrugRepV_4614Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
19853271
DrugRepV_4615Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
19853271
DrugRepV_4616Promazine
Nervous System
Psychomotor agitation
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Vet approved
19853271
DrugRepV_4617Promazine
Nervous System
Psychomotor agitation
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Vet approved
19853271
DrugRepV_4618Calpain VI inhibitor
NA
NA
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4619Calpain VI inhibitor
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4620Calpain IV inhibitor
NA
NA
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4621Calpain IV inhibitor
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4622Infergen
Anticancer
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcom
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
19853271
DrugRepV_4623Infergen
Anticancer
Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcom
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
19853271
DrugRepV_4624Ampligen
NA
NA
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4625Ampligen
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4626UDA
NA
NA
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4627UDA
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4628EP128533
NA
NA
Severe acute respiratory syndrome coronavirus
v2163
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4629EP128533
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19853271
DrugRepV_4634TG-0205221
NA
SARS coronavirus
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16884309
DrugRepV_4635ethyl (2E,4S)-4-[(2S)-3-(4-fluorophenyl)-2-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)formamido]butanamido]propanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16884309
DrugRepV_4636ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-3-phenylpropanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16884309
DrugRepV_4637ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16884309
DrugRepV_4638ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(tert-butoxy)butanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
NA
NA
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16884309
DrugRepV_4639TG-0205221
NA
SARS coronavirus
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease (6.4 Log10)
NA
16884309
DrugRepV_4640TG-0205221
NA
SARS coronavirus
Severe acute respiratory syndrome coronavirus
Urbani
NA
Cytopathic effect (CPE) assay
Decrease
NA
16884309
DrugRepV_46415CI-IS-AC
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4642SPIII-5H
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4643SPIII-5Cl
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4644SPIII-5Br
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4645SPIII-5F
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4646SPIII-5Me
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4647SPIII-NA
NA
NA
Severe acute respiratory syndrome coronavirus
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
20390088
DrugRepV_4714Nutlin-3
NA
NA
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
29795047
DrugRepV_4715Hydroxyzine pamoate
Nervous System
Anxiety | Tension
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
29795047
DrugRepV_4716Amodiaquine Dihydrochloride
Antiparasitic products, Insectisides and Repellents
Malaria
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
29795047
DrugRepV_4717Amodiaquine Dihydrochloride Dihydrate
Antiparasitic products, Insectisides and Repellents
Malaria
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
29795047
DrugRepV_4718Chloroquine Diphosphate
Antiparasitic products, Insectisides and Repellents
Parasitic infections
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational, Vet approved
29795047
DrugRepV_4719Hydroxychloroquine Sulfate
Antiparasitic products, Insectisides and Repellents
Malaria
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
29795047
DrugRepV_4720Saracatinib
Anticancer
Osteosarcoma | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
29795047
DrugRepV_4721Sotrastaurin
Anticancer
Uveal Melanoma | Richter Syndrome | Prolymphocytic Leukemia | Recurrent Mantle Cell Lymphoma Recurrent Small Lymphocytic Lymphoma
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
29795047
DrugRepV_4722Acetophenazine Maleate
Nervous System
NA
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
29795047
DrugRepV_4723Dosulepin Hydrochloride
Nervous System
Psychosis
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
29795047
DrugRepV_4724Methotrimeprazine Maleate Salt
NA
NA
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
29795047
DrugRepV_4725N1-(4-pyridyl)-2-chloro-5-nitrobenzamide
NA
NA
Middle East respiratory syndrome coronavirus
EMC/2012 strain
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
29795047
DrugRepV_5953NITD008
Antiviral
NA
Dengue virus
New Guinea C
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19918064
DrugRepV_5963NITD008
Antiviral
NA
Dengue virus
New Guinea C
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
19918064
DrugRepV_5969ZX-2401
NA
Rhinovirus 1A | Rhinovirus 30 | Rhinovirus 13 | Rhinovirus 8 | Rhinovirus 2
Dengue virus
New Guinea
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
16199098
DrugRepV_7241Favipiravir
Antiviral
Influenza virus
Yellow fever virus
17D
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
27736754
DrugRepV_7330CW-33
NA
NA
Japanese encephalitis virus
T1P1
Pathway
Cytopathic effect (CPE) assay
Decrease
NA
27563890
DrugRepV_7331CW-33
NA
NA
Japanese encephalitis virus
T1P1
Pathway
Cytopathic effect (CPE) assay
Decrease
NA
27563890
DrugRepV_7387SCH16-Ribavirin
NA
NA
Japanese encephalitis virus
P20778
Pathway
Cytopathic effect (CPE) assay
Decrease
NA
22738253
DrugRepV_7388SCH16-Mycophenolic acid
NA
NA
Japanese encephalitis virus
P20778
Pathway
Cytopathic effect (CPE) assay
Decrease
NA
22738253
DrugRepV_7525Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/KY/14-18953
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7526Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/MO/14-18949
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7527Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/MO/14-18947
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7528Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/IL/14-18952
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7529Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/IL/14-18956
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7530Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/KY/14-18953
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7531Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/KY/14-18953
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7532Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/KY/14-18953
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7533Telaprevir
Antiinfectives For Systemic Use
Hepatitis C virus
Enterovirus
US/KY/14-18953
Pathway
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
30674624
DrugRepV_7608Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
SARS Coronavirus-2
?CoV/KOR/KCDC03/2020)
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32438446
DrugRepV_7609Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
SARS Coronavirus-2
?CoV/KOR/KCDC03/2020)
NA
Cytopathic effect (CPE) assay
Decrease (90 %)
Approved
32438446
DrugRepV_7617Remdesivir
Antiviral
Hepatitis C | Ebola
SARS Coronavirus-2
SARS-CoV-2 (?CoV/KOR/KCDC03/2020
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
32438446
DrugRepV_7647Lopinavir
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
SARS Coronavirus-2
?CoV/KOR/KCDC03/2020)
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32438446
DrugRepV_7648Lopinavir
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
SARS Coronavirus-2
?CoV/KOR/KCDC03/2020)
NA
Cytopathic effect (CPE) assay
Decrease (90 %)
Approved
32438446
DrugRepV_7672Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
SARS Coronavirus-2
NA
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32511355
DrugRepV_7673ROC-325
NA
NA
SARS Coronavirus-2
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
32511355
DrugRepV_7674Mefloquine
Antiparasitic products, Insectisides and Repellents
Malaria
SARS Coronavirus-2
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
32511355
DrugRepV_7675Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
SARS Coronavirus-2
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32511355
DrugRepV_7676Hycanthone
Antischistosomal
Parasitic infections
SARS Coronavirus-2
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
32511355
DrugRepV_7677Clomipramine
Nervous System
Depression, schizophrenia, Tourette disorder
SARS Coronavirus-2
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32511355
DrugRepV_8325Remdesivir
Antiviral
Hepatitis C | Ebola
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
32429580
DrugRepV_8326Tenofovir
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved, Investigational
32429580
DrugRepV_83274-ethynyl-2-fluoro-2-deoxyadenosine
NA
NA
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
32429580
DrugRepV_8328Alovudine
NA
HIV
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Investigational
32429580
DrugRepV_83295-O-(12-thioethydodecanoyl)FLT
NA
NA
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
32429580
DrugRepV_8330Lamivudine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome | Hepatitis B virus
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32429580
DrugRepV_83315-O-(tetradecanoyl)3TC
NA
NA
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
32429580
DrugRepV_8332Emtricitabine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
32429580
DrugRepV_83335-O-(tetradecanoyl)FTC
NA
NA
SARS Coronavirus-2
Experimental
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
NA
32429580
DrugRepV_8459Berberine
NA
Parasitic and fungal infection
Enterovirus
H
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28081706
DrugRepV_8460Berberine
NA
Parasitic and fungal infection
Enterovirus
SHZH98
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28081706
DrugRepV_8461Berberine
NA
Parasitic and fungal infection
Enterovirus
JS-52
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28081706
DrugRepV_8462Berberine
NA
Parasitic and fungal infection
Enterovirus
BrCr
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Approved
28081706
DrugRepV_8463Pirodavir
NA
Picronavirus infection
Enterovirus
H
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
28081706
DrugRepV_8464Pirodavir
NA
Picronavirus infection
Enterovirus
SHZH98
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
28081706
DrugRepV_8465Pirodavir
NA
Picronavirus infection
Enterovirus
JS-52
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
28081706
DrugRepV_8466Pirodavir
NA
Picronavirus infection
Enterovirus
BrCr
NA
Cytopathic effect (CPE) assay
Decrease (50 %)
Experimental
28081706